DNA storage

DNA-based data storage has emerged as a promising solution to the exponentially increasing demand for information storage in the modern era due to its massive information density. However, limitations such as high cost in current DNA writing and reading technologies are rendering its use financially infeasible. To contribute to the new revolution of information storage, we research solutions that augment the practicality of DNA as a storage medium. This includes the use of degenerate DNA bases that can expand the alphabet to which binary information could be encoded, ultimately reducing the amount of DNA needed. Another innovation is the DNA micro-disks which can be read many times without the loss of information while simultaneously compartmentalizing stored information, allowing for random access. These pragmatic solutions can greatly aid in DNA data storage reaching its full potential in the near future.

• YeongjaeChoi, Taehoon Ryu, Amos C. Lee, Hansol Choi, Hansaem Lee, Jaejun Park, Suk-Heung Song, Seojoo Kim, Hyeli Kim, Wook Park & Sunghoon Kwon (2019). High information capacity DNA-based data storage with augmented encoding characters using degenerate bases. Scientific reports

• Yeongjae Choi, Hyung Jong Bae, Amos C. Lee, Hansol Choi, Daewon Lee, Taehoon Ryu, Jinwoo Hyun, Seojoo Kim, Hyeli Kim, Suk‐Heung Song, Kibeom Kim, Wook Park & Sunghoon Kwon (2020). DNA Micro‐Disks for the Management of DNA‐Based Data Storage with Index and Write‐Once–Read‐Many (WORM) Memory Features. Advanced Materials