Encoded microparticle
Optical engineering using functional particles
The use of multiplexed high-throughput bioassays in applications such as drug discovery and clinical diagnostics has the potential to greatly expand the scope of experiments and data generation. We propose various encoded particle fabrication and design methodologies including shape and color encoding which make the resulting particles an exceptional tool for such uses. Our color encoding technology can create vivid, free-floating structural colored particles with multi-axis rotational control using a color-tunable magnetic material through a new printing method. Our color-barcoded magnetic microparticles offer a coding capacity easily into the billions with distinct magnetic handling capabilities. A DNA hybridization assay has been performed using the color-barcoded magnetic microparticles to demonstrate its multiplexing capabilities.
- Howon Lee, Junhoi Kim, Hyoki Kim, Jiyun Kim & Sunghoon Kwon (2010). Colour-barcoded magnetic microparticles for multiplexed bioassays. Nature materials
- Lily Nari Kim, Mira Kim, Keumsim Jung, Hyung Jong Bae, Jisung Jang, Yushin Jung, Jiyun Kim and Sunghoon Kwon (2015). Shape-encoded silica microparticles for multiplexed bioassays. Chemical Communications
- Gustav Svedberg, Yunjin Jeong, Hunjong Na, Jisung Jang, Peter Nilsson, Sunghoon Kwon, Jesper Gantelius & Helene Andersson Svahn (2017).Towards encoded particles for highly multiplexed colorimetric point of care autoantibody detection. Lab on a Chip
Particle fabrication using microfluidics
Optofluidic maskless lithography is a technique that can synthesize free-floating microstructures in microfluidic channels at the desired time and location within the field of view of the lithography system. By uniquely combining the concept of maskless and continuous-flow lithography techniques and microfluidic channels, we experimentally demonstrate real-time control of the in-situ polymerization process to dynamically synthesize extruded polymeric microstructures.
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Su Eun Chung, Wook Park, Hyungsung Park, Kyoungsik Yu, Namkyoo Park & Sunghoon Kwon (2007). Optofluidic maskless lithography system for real-time synthesis of photopolymerized microstructures in microfluidic channels. Applied Physics Letters
4D printing
By leveraging the advantages of simple, inexpensive and intuitive 2D printing, we developed a “pen-based 4D printing” that enables the transformation of pen-drawn 2D precursors into 3D geometries. 2D-to-3D transformation of pen drawings is facilitated by surface tension–driven capillary peeling and floating of dried ink film when the drawing is dipped into an aqueous monomer solution. By utilizing this printing method, we could convenient hydrogel structures with complex geometries, with the intention of expanding to more rigid materials in the future. Our approach benefits from both freestyle usability and high throughput fabrication via pen drawing and roll-to-roll processing. Focusing more on 'simple fabrication', we envision soft robots with complex motion without complex fabrication steps.
- Seo Woo Song, Sumin Lee, Jun Kyu Choe, Na-Hyang Kim, Junwon Kang, Amos Chungwon Lee, Yeongjae Choi, Ahyoun Choi, Yunjin Jeong, Wooseok Lee, Ju-Young Kim, Sunghoon Kwon & Jiyun Kim. (2021). Direct 2D-to-3D transformation of pen drawings. Science Advances
- Seo Woo Song, Sumin Lee, Jun Kyu Choe, Amos Chungwon Lee, Kyoungseob Shin, Junwon Kang, Gyeongjun Kim, Huiran Yeom, Yeongjae Choi, Sunghoon Kwon & Jiyun Kim. (2023). Pen-drawn Marangoni swimmer. Nature communications